From: "seminar" <seminar@psb.vib-ugent.be>
To: meetings@psb.vib-ugent.be
Sent: Wednesday, March 19, 2025 8:35:55 AM
Subject: PSB Seminar Towards the identification of novel metal- or thiol-based mechanisms in plants via the biochemical characterization of TRX-like proteins

| PSB Seminar Towards the identification of novel metal- or thiol-based mechanisms in plants via the biochemical characterization of TRX-like proteins Nicolas Rouhier Université de Lorraine France Where: Jozef Shell Seminar room - VIB-UGent Center for Plant Systems Biology Ghent University Technologiepark 71 - 9052 Ghent - Belgium Tel. +32(0)9 331 38 00 www.psb.ugent.be When: 03-APR-2025@11:00 Invited by Yves Van de Peer , Frank Van Breusegem Photosynthetic organisms have a high diversity of proteins belonging to the thioredoxin (TRX) superfamily. It comprises more than 150 proteins distributed in different families and classes, including in particular thioredoxins, glutaredoxins, protein disulfide isomerases, thiol peroxidases or glutathione transferases, which share the TRX structural fold. Many of them have one or two redox-active cysteines and a characteristic cis-proline at specific positions, but also additional domains or secondary structures at either end or inserted into the protein core. With the aim of further describing the TRX superfamily in plants, we identified a set of 17 atypical TRX-like proteins from Arabidopsis thaliana, which have not been considered before. The in silico analyses revealed that they differ by their active-site signature and structural features and that they are spread in eight distinct classes. To delineate the possible functions of these novel TRX-like proteins, we combined biochemical and structural analyses of recombinant proteins together with cellular approaches to determine their subcellular localizations. Recent data obtained on specific representatives will be presented. Jozef Shell Seminar room - VIB-UGent Center for Plant Systems Biology Ghent University Technologiepark 71 - 9052 Ghent - Belgium Tel. +32(0)9 331 38 00 www.psb.ugent.be If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/listinfo/seminars