[BBC] [Gtpb] BFG12-Bioinformatics and Functional Genomics using R and Bioconductor
Pedro Fernandes
pfern at igc.gulbenkian.pt
Sun May 27 12:29:35 CEST 2012
Please excuse us for cross or duplicated messages
ANNOUNCEMENT / REMINDER
BFG12
Bioinformatics and Functional Genomics using R and Bioconductor
with Javier de las Rivas and Celia Fontanillo
from Universidad de Salamanca (USAL), Salamanca, ES and
Consejo Superior de Investigaciones Científicas (CSIC)
IMPORTANT DATES for this Course
Deadline for applications: June 11th 2012
Notification of acceptance dates:
EARLY: June 8th 2012 (on special request, see Application)
NORMAL: June 14th 2012
Course date: June 18th to June 20th 2012
Course description:
This is a practical course on Bioinformatics applied to analysis of
Gene expression and Genomic data using mainly R and Bioconductor tools
and algorithms. The course will focus in the use of robust methods to
analyse microarray datasets, mainly from Affymetrix platform and from
clinical-biomedical studies, integrating several strategies to achieve
an optimum construction and analyses of gene expression profiles. The
Course will be mostly practical using computers and prepared protocols.
It will be divided in three major sessions:
1. Gene Expression Profiling. Microarrays genome-wide expression data
integration, normalization, gene-based signal calculation,
differential expression (using different algorithms: SAM, Bayesian and
Limma) and clustering. Databases that integrate gene signatures.
2. Classification and Prediction using genomic data. Application of
machine learning techniques to the analysis of gene expression data to
allow classification of different states or different diseases
subtypes. Error calculations. Class-prediction using de novo samples.
3. Gene Functional Enrichment. Gene list functional annotation using
tools for statistical enrichment based on multiple concurrent
annotation. Application of algorithms that measure outcome and
response to assign specific functions to gene expression datasets.
Target Audience
Researchers in Biology and Biomedical areas (PhD students, PostDocs or
Senior) working with genomic and gene expression data or with gene
lists in general, that what to learn useful and powerful tools and
methods for bioinformatic analysis.
Course Pre-requisites
Basic familiarity with genomic data and bioinformatics data resources.
Minimum familiarity with R (although most scripts and command lines
will be provided with written tutorials).
Futher details, including application instructions available at
http://gtpb.igc.gulbenkian.pt/bicourses/BFG12/
thank you for your interest
Pedro Fernandes
GTPB Coordinator
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