[BBC] [Gtpb] Bioinformatics Training Course CSDM13 - Reminder
Pedro Fernandes
pfern at igc.gulbenkian.pt
Mon Nov 11 08:58:41 CET 2013
Course Announcement
(Reminder)
Applications are open for:
CSDM13
"Chromosome structure determination using modeling and Hi-C data"
with Davide Baù and François Serra (CNAG and CRG, Barcelona)
IMPORTANT DATES for this Course
Deadline for applications: November 20th 2013
Notification of acceptance within 72 hours of application
Course date: November 27th to November 29th 2013
More details at the course website
http://gtpb.igc.gulbenkian.pt/bicourses/CSDM13/
*Course description*
The sequence of a genome alone does not carry enough information to
fully understand how genomic processes are carried out in the cell
nucleus; to achieve this, the knowledge of the three-dimensional (3D)
architecture of a genome is necessary. Advances in genomic
technologies and the development of new analytical methods, such as
3C-based methods, have allowed getting insights at unprecedented
resolution into how the genome is organized. Recently, it has been
shown that chromatin is organized in Topologically Associating Domains
(TADs), large interaction domains that appear to be conserved among
different cell types.
In this course, participants will learn to use TADBit, a software for
the analysis and 3D modeling of Topologically Associated Domains
(TADs) and genomes. TADBit is based on a computational module of the
Integrative Modeling Platform (IMP,
http://www.integrativemodeling.org) that uses chromosome conformation
capture data to determine the 3D architecture of genomic domains and
entire genomes at unprecedented resolutions.
Participants can bring-in specific biological questions and/or their
on data to work on during the course.
*Target Audience*
The course is oriented to experimental researchers with minimal
computational skills, at the graduate and post-graduate levels. It is
also suitable for bioinformatics developers at all levels. We
anticipate that this course is attended by people with several types
of interests in genome organization. It is likely that they may also
aim at getting involved in generating Hi-C data for chromosome
structure determination and that they want to model its 3D
representation, but that does not need to be the case for all the
participants: they may, for example, just want to explore publicly
available data.
--
--
Pedro Fernandes
Instituto Gulbenkian de Ciência
Apartado 14
2781-901 OEIRAS
PORTUGAL
Tel +351 21 4407912
http://gtpb.igc.gulbenkian.pt
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