[BBC] BioSB Course: In silico life: constraint-based modelling at genome scale, May 9-11 2016, Amsterdam

[Femke Francissen]

*BioSB Course: In silico life: constraint-based modelling at genome scale*

*Date:* May 9-11, 2016
*Location:* Amsterdam
*Course Coordinator:* Bas Teusink and Brett Olivier, Vrije Universiteit
Amsterdam
*Website:*
http://biosb.nl/education/course-portfolio-2/course-constraint-based-modelling-course/
*Registration:*
http://biosb.nl/education/course-portfolio-2/course-constraint-based-modelling-course/enrollment-constraint-based-modelling-course/

Constraint-based modelling is a powerful modelling methodology that is
being used to model a diverse range of biological phenomena. These include
both fundamental and applied questions relevant to biotechnology,
microbiology and medicine. Central to constraint-based modelling is the use
of a genome-scale reconstructions (GSR’s) that maps out the metabolism of a
cell as a biochemical reaction network.

In this course you will be introduced to:

   - techniques for the construction of a working GSR: tools, tricks and
   pitfalls
   - the underlying mathematical definition and description of a
   constraint-based model
   - methods for interrogating models and interpreting results, such as
   Flux Balance Analysis and Flux Variability Analysis
   - software and standards

The preliminary course structure will be to divide each day into both
lectures and practical sessions so that learned theory can immediately be
applied in silico.

*Target Audience*
Constraint-based modelling is a rapidly growing field that is being use in
both fundamental and applied research and biotechnology. It sits at the
intersection between quantitative metabolic modelling, bioinformatics and
cellular physiology and, as such, is an example of systems biology at work.
While participants would benefit from some knowledge of either quantitative
modelling, bioinformatics or microbial physiology this is not required.
This includes, for example, scientists working in a laboratory and wanting
to learn more about building or using genome-scale models, as well as,
those who have used basic FBA, but want to know how else it can be applied
to their research.

The course is part of the Education Programme of BioSB, the Netherlands
Bioinformatics and Systems Biology Research School, which offers training
and education for in bioinformatics and systems biology. More information
about BioSB can be found at www.biosb.nl.




Kind regards,
*​*
*​*
*Femke Francissen*
Community manager BioSB

BioSB Research School
Visiting address: Geert Grooteplein 28, route 260, 6525 GA Nijmegen
Postal address: P.O. box 9101, route 260, 6500 HB Nijmegen

E-mail: femke.francissen at biosb.nl
Tel: +31 24 36 19 500
Mobile: +31 6 17 90 4888
Skype: femke.francissen
Website: www.biosb.nl
LinkedIn link <http://nl.linkedin.com/in/femkefrancissen>
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