[BBC] [Gtpb] REMINDER Structural Modeling for Large Macromolecular Complexes - SMLMC14 in Oeiras, Portugal

[Pedro Fernandes]

                     GTPB Reminder

Applications are open for another Bioinformatics Training course:

SMLMC14
Structural Modeling for Large Macromolecular Complexes
with Joanna Kasprzak and Grzegorz Chojnowski

    IMPORTANT DATES for this Course
    Deadline for applications: May 15th 2014
    Latest notification of acceptance: May 17th 2014
    Course date: June 11th - June 13th 2014


Course description
One of the major challenges in structural biology is to determine the   
  structures of macromolecular complexes and to understand their  
function and mechanism of action. However, structural characterisation  
of macromolecular assemblies is very difficult. To begin addressing  
this problem, we have developed PyRy3D.
In a nutshell, PyRy3D employs a hybrid computational approach that    
incorporates spatial information from a variety of experimental  
methods into the modelling procedure to build low-resolution models of  
large macromolecular complexes. The PyRy3D model building procedure    
uses a Monte Carlo approach to sample the solutions-space. It uses    
spatial restraints to define components interacting with each other,  
and a simple scoring function is applied to pack them tightly into  
contours of the entire complex (e.g. cryoEM density maps).

More details at
http://gtpb.igc.gulbenkian.pt/bicourses/SMLMC14/

Thank you for your interest!

Pedro Fernandes
GTPB Coordinator

-- 
Pedro Fernandes
Instituto Gulbenkian de Ciência
Apartado 14
2781-901 OEIRAS
PORTUGAL
Tel +351 21 4407912
http://gtpb.igc.gulbenkian.pt

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