[BBC] Job announcement: Postdoc position in Cancer Bioinformatics

Can Kesmir c.kesmir at uu.nl
Wed Jun 24 17:05:46 CEST 2015


Dear all

We have an exciting postdoc position available in cancer bioinformatics, 
that should be filled in as soon as possible.

*Job description*

The postdoc will be part of a joint international effort to implement 
personalized immunotherapy, targeting unique tumor associated mutations 
in patients. This is an exciting position at the crossroad of the 
blooming field of cancer genomics, and immunological bioinformatics.

The postdoc will be working on two main projects: 1) evaluation and 
further development of existing models to predict the likelihood that a 
presented tumor mutation (in the form of a peptide-MHC complex) is 
recognized by the patient’s immune system, and 2) based on the primary 
sequence information of T cell receptors, predict their most likely 
ligands (e.g., mutations found in the individual patients). These 
innovative and ambitious projects will be performed in close 
collaboration with Prof. Ton Schumacher from Dutch Cancer Institute (NKI).

The position is part of the EU Horizon2020 project called "APERIM: 
Advanced bioinformatics platform for PERsonalised cancer Immunotherapy” 
(H2020-PHC-2014), consisting of eight academic partners and three companies.

*Qualifications*

We are looking for a bioinformatician at the postdoc level with a keen 
interest in immunology and/or cancer. The position can be converted into 
a PhD student in case we have an excellent candidate. Applications from 
cancer immunologists with some computational experience are highly welcome.
*
Offer*

The candidate is offered a full-time position for three years.The salary 
is supplemented with a holiday bonus of 8% and an end-of-year bonus of 
8,3% per year. In addition we offer: a pension scheme, a partially paid 
parental leave, flexible employment conditions 
<http://www.uu.nl/EN/informationfor/jobseekers/Working-for-Utrecht-University/terms-of-employment/Pages/default.aspx>. 
Conditions are based on the Collective Labour Agreement Dutch 
Universities. The research group will provide the candidate with 
necessary support on all aspects of the project.

*About the organisation*

Utrecht University <http://www.uu.nl/en> has great ambitions for its 
teaching quality and study success rates. This also applies to its clear 
research profiles which are centred around four themes: Dynamics of 
Youth, Institutions, Life Sciences and Sustainability. Utrecht 
University plays a prominent role in our society and contributes to 
finding the answers to topical and future societal issues.

The Faculty of Science 
<http://www.uu.nl/en/organisation/faculty-of-science> consists of six 
departments: Biology, Pharmaceutical Sciences, Information and Computing 
Sciences, Physics and Astronomy, Chemistry and Mathematics. The Faculty 
is home to 3500 students and nearly 2000 staff and is internationally 
renowned for the quality of its research. The Faculty's academic 
programmes reflect developments in today's society.

The theoretical biology and bioinformatics <http://tbb.bio.uu.nl/> (TBB) 
group at the Biology department of Utrecht University employs 
computational and mathematical models and bioinformatics to perform 
fundamental biological research in a variety of biological disciplines, 
and part of the group is specialized in immunology (Prof. Rob de Boer 
and Dr. Can Kesmir). We have long a standing expertise in modeling the 
immune system and in applying bioinformatics (mainly data-driven 
methods) to predict the specificity of the immune responses. The group 
is part of the Institute of Biodynamics and Biocomplexity 
<http://www.ibb-uu.nl/> (IBB <http://www.ibb-uu.nl/>), embedded in one 
of the largest Biology departments in the Netherlands (>200 new students 
per year). We are part of the Utrecht Center for Quantitative Immunology 
<http://tbb.bio.uu.nl/ucqi>(UCQI <http://tbb.bio.uu.nl/ucqi>), which 
brings together an experienced collaborative team of immunologists, 
bioinformaticians, and mathematical modelers. This unique position 
allows daily collaboration with wet lab immunologists and biologists.

The group teaches modeling and bioinformatics to biology students at the 
bachelor and master level. PhD students in the group have diverse 
backgrounds ranging from biology, physics to mathematics, and typically 
half of them are from abroad. The IBB focuses on molecular life 
sciences, and is collaborating with other departments of the Faculty of 
Science, the Faculty of Medicine, and the Hubrecht Institute in Utrecht. 
UCQI is a joint effort between Utrecht University and the Utrecht 
Medical Center.


*How to apply?*

Application deadline is 1st of July. Please use the following link to 
apply:

https://lnkd.in/dPDXR_7

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