[BBC] Job opening: VIB Postdoc in Plant Single Cell Biology

[Yvan Saeys]

A postdoctoral research position in the De Rybel lab (VIB) in the area 
of single cell transcriptomics in crop plants is available. This 
position is a close collaboration between the De Rybel and Saeys labs at 
VIB in collaboration with BASF as industrial partner in the framework of 
an approved VLAIO project. The successful candidate will adapt existing 
wet lab single cell transcriptomics methodologies to crop plant species 
and initiate statistical analysis of this data. As such, this position 
entails the integration of both wet lab and dry lab into one 
collaborative project.

About the Partners
The De Rybel lab at the VIB‐UGent Center for Plant Systems Biology (PSB) 
has a key interest in understanding cell division orientation in plants 
and how this process contributes to vascular proliferation. The lab has 
a long-standing expertise in using bulk RNA-sequencing to uncover 
transcriptional networks during plant developmental processes. More 
recently, a strong investment was made to establish single cell RNA-seq 
(scRNA-seq) workflows to further increase resolution at spatial and 
temporal level. In this case, the wet-lab expertise was developed by the 
De Rybel lab, while the bio-infomatics expertise and all data analysis 
was optimised in the Saeys lab.

The Saeys lab at the VIB-UGent Center for Inflammation Research (IRC) 
studies the design and application of data mining and machine learning 
techniques for biomedical applications.  The lab is renowned for its 
research on single-cell technologies, including flow and mass cytometry, 
single-cell RNA sequencing, and is currently pioneering novel 
single-cell technologies including spatial transcriptomics and 
single-cell multi-omics (e.g. CITE-seq).

The BASF Innovation Center in Gent aims to deliver innovative solutions 
for BASFs seed business by developing valuable traits for various crops 
through biotechnology solutions and modern breeding techniques. The 
activities of the Innovation Center cover all aspects involved with the 
R&D process, from the initial stages of research to life cycle 
management, or as we call it, from the lab to the field. The Innovation 
Center employs a workforce of approximately 400 from 20 different 
countries at state-of-the-art laboratories space for plant biotechnology 
research in Zwijnaarde and greenhouse and breeding installations in 
Astene, Zwijnaarde, and Bottelare.

Your project
Embedded in the De Rybel lab at VIB and in close collaboration with the 
Saeys lab at VIB and BASF as industrial partner, you will support the 
implementation, analysis and ongoing development of single cell 
transcriptome data-sets in the context of plant biotechnology.  As a 
true go-between these collaborative groups, you will work at the 
intersection between the experimental scientists and the computational 
scientists.
You will be involved in the wet lab data generation pipeline with the De 
Rybel lab, BASF and VIB core facilities to further optimize the existing 
workflows.  You will be involved in the dry lab data analysis pipeline 
with the Saeys lab and BASF to establish and optimise the bio-informatic 
workflows.

Profile

  * You have a PhD in Plant biotechnology with a strong interest or
    experience in bioinformatics/computational biology; OR you have a
    PhD in bioinformatics/computational biology with a clear experience
    in plant biotechnology.
  * You have good Linux/command line skills and you are experienced with
    R and/or python programming
  * You have hands-on experience with (single cell) RNA sequencing or
    other NGS workflows.
  * Attention to detail, accurate reasoning and problem-solving skills
    are needed.
  * You must be able to communicate effectively (written and spoken) in
    English and act as go-between person between the research groups and
    the company
  * Ability to work well independently and within a team environment
  * You have strong time management and communication skills to balance
    multiple experiments between several collaborators
  * Having a multidisciplinary background in laboratory work and
    bioinformatics is requested. Experience with web technologies (such
    as PHP, HTML, CSS, Javascript, vue.js or Laravel) is a plus but not
    required.

We offer

  * A full time post-doc position in the De Rybel lab for 3 years within
    the framework of a successful VLAIO grant application between the De
    Rybel lab, the Saeys lab and BASF (Starting Date: September 2020)
  * Working at the interface between Academic (VIB) and Industrial
    (BASF) teams with a can-do-attitude and a strong on-going collaboration
  * Entrance into our Plant Single Cell Platform with access to
    state-of-the-art VIB Core Facilities.
  * The opportunity to develop as a single-cell transcriptomics expert
    in the plant field and within a strong network of both scientific
    and industrial collaborators.

How to apply?
For more information contact Bert De Rybel. Please complete the online 
application procedure <https://jobso.id/cqo6> and include a detailed CV 
incl. list of publications, a motivation letter and the contact 
information of three referees.

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Prof. dr. Yvan Saeys
VIB Group Leader Data mining and modeling for biomedicine

UGent Department of Applied Mathematics, Computer Science and Statistics
Krijgslaan 281, S9, B-9000 Gent
Inflammation Research Center, a VIB-UGent Department
Technologiepark-Zwijnaarde 71 , B-9052 Zwijnaarde , Belgium

Tel : +32(0)9 331 37 40 Fax : +32(0)9 221 76 73
Mailto: yvan.saeys at ugent.be   http://www.dambi.ugent.be
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