[Seminars] PSB event reminder
contact at psb.vib-ugent.be
contact at psb.vib-ugent.be
Tue Feb 21 11:10:01 CET 2012
Calendar Name: seminars
Scheduled for: Thursday, February 23 2012, 11:00 - 12:30
Event text: Prof Marnik Vuylsteke
VIB, Dept. of Plant Systems Biology
Ghent University
Gent
BELGIUM
Details: Genome-wide association study of endoreduplication in
Arabidopsis thaliana: the first harvest"
ABSTRACT
The genome-wide association approach (GWAS) overcomes
several limitations of traditional linkage mapping by
(i) providing higher mapping resolution, often to the
gene level, and (ii) using large samples of populations
in which commonly occurring genetic variations can be
associated with phenotypic variation. The availability
of thousands of single-nucleotide polymorphisms (SNPs)
allows whole-genome scans to identify haplotype blocks
significantly associated with quantitative variation. We
have applied this GWAS approach, in combination with
linkage mapping, to identify novel genes involved in
endoreduplication in Arabidopsis thaliana.
Endoreduplication is the process where a cell replicates
its genome without mitosis and cytokinesis. Here, in
this presentation, I will discuss the first harvest of
this GWAS study.
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