[Seminars] PSB event reminder

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Calendar Name: seminars
Scheduled for: Thursday, June 6 2013, 11:00 - 12:30
Event text:    Dr Markus Teige
	       
	       Department of Molecular Systems Biology (MOSYS)
	       Vienna University
	       
	       Vienna
	       AUSTRIA
Details:       "Multiple phosphorylations by multiple kinases at
	       multiple locations- how to keep track on cellular
	       signalling in plants?"
	       
	       ABSTRACT
	       Protein phosphorylation is one key regulatory principle
	       in all living organisms: about 30% of all cellular
	       proteins are - at least occasionally - phosphorylated
	       and sequenced genomes encode about 500 to 1000 protein
	       kinases. Moreover, some proteins can be phosphorylated
	       by different kinases at multiple sites, which makes it
	       even more challenging to keep an overview on these
	       regulatory processes. One approach, which helps to get
	       an overview on these diverse processes is to ask where
	       and when these phosphorylation events occur. Many of
	       them will be triggered by specific signals and also take
	       place only in distinct subcellular localizations.
	       Therefore I will start with the discussion of protein
	       kinases, which are involved in the (salt-) stress
	       response at different membrane systems, but which are
	       also active in the cytosol and the nucleus. At all
	       places, there is cross-talk with other signalling
	       pathways and different pathways merge at targets, which
	       are phosphorylated by different kinases. I will present
	       a bZIP transcription factor as one example to illustrate
	       how this could serve as integration point of different
	       signalling pathways, which are used in response to
	       different stresses.

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