AI Engineer / Bioinformatician – AI for Drug Discovery Join the *AI for Genome Interpretation (AI4GI)*group at *IGMM-CNRS, Montpellier*, for a 13-month engineer position with the possibility of renewal for up to 3 additional years. You will work at the intersection of *machine learning, bioinformatics, chemoinformatics and cancer biology*, in a collaboration between Raimondi and Hahne laboratories. The goal is to develop AI methods to predict drug responses in *treatment-resistant CMS4 colorectal cancer*and accelerate the discovery of new therapeutic molecules. Your work will include: * Developing *novel PyTorch-based machine learning methods*for drug-response prediction. * Integrating *pharmacogenomic, molecular and phenotypic data*from resources such as GDSC, DepMap and CCLE. * Developing molecular representations using *chemoinformatics, molecular fingerprints and graph-based approaches*. * Building an *Active Learning, experiment-in-the-loop framework*that selects the most informative compounds for experimental validation. * Applying the resulting models to the *virtual screening of 78 billion compounds*in the Enamine REAL chemical library. * Working closely with experimental cancer biologists to iteratively improve the computational models. We are looking for someone with strong *Python and machine learning skills*, a solid understanding of *mathematics, statistics and deep learning*, and familiarity with scientific computing and Linux. Experience in *bioinformatics, chemoinformatics, pharmacogenomics, drug-response prediction, GNNs, Active Learning, uncertainty estimation or HPC/GPU computing*is a strong advantage. This is an opportunity to develop *new AI methodologies with direct applications to drug discovery*, while working in a highly interdisciplinary and international research environment at IGMM-CNRS in Montpellier. *Contract:*13 months, renewable up to 3 years *Salary:* depending on experience, from around €2,521 gross/month *Benefits:*44 days annual leave/RTT, remote-working support, 75% public transport reimbursement and mobility allowance up to €300 *_Candidates can apply at this link_* https://emploi.cnrs.fr/Offres/CDD/UMR5535-SARADE-117/Default.aspx