*A phylostratigraphy approach to uncover the genomic history of major adaptations in metazoan lineages* * Tomislav Domazet-Los(o, Josip Brajkovic' and Diethard Tautz* Macroevolutionary trends traditionally are studied by fossil analysis, comparative morphology or evo-devo approaches. With the availability of genome sequences and associated data from an increasing diversity of taxa, it is now possible to add an additional level of analysis: genomic phylostratigraphy. As an example of this approach, we use a phylogenetic framework and embryo expression data from /Drosophila/ to show that grouping genes by their phylogenetic origin can uncover footprints of important adaptive events in evolution. -- ================================================================== Cindy Martens VIB Department of Plant Systems Biology, Ghent University Technologiepark 927, 9052 Gent, BELGIUM Tel: +32 (0)9 331 38 22 Fax: +32 (0)9 331 38 09 E-mail: cindy.martens@psb.ugent.be Website: http://bioinformatics.psb.ugent.be/ ==================================================================