fyi http://genefriends.org/ GeneFriends is a functional genomics tool aimed at biologists and clinicians. It is based on a gene co-expression map that describes which genes tend to be activated (increase in expression) and deactivated (decrease in expression) simultaneously in a large number of microarray datasets. Because the microarray datasets come from a wide range of conditions, the co-expression map reflects which genes in general tend to be activated simultaneously and are thus under similar transcriptional regulation. This information can be used statistically, using a guilt-by-association approach, to identify and prioritize novel candidate genes involved in biological processes and complex diseases for which a seed list of genes associated with that disease or process is available. It can also be used to gain insights on genes of unknown function by looking at which genes they are co-expressed with. -- ========================================================== Bram Slabbinck, PhD Bioinformatics & Systems Biology Division VIB Department of Plant Systems Biology, UGent Technologiepark 927, 9052 Gent, BELGIUM Tel:+32 (0)9 33 13 537 Fax:+32 (0)9 33 13 809 Email: Bram.Slabbinck@psb.ugent.be WWW: http://bioinformatics.psb.ugent.be ========================================================== Services and consulting in bioinformatics http://www.arctix.be ========================================================== Please consider the environment before printing this email