- Seminars - maillist.psb.ugent.be

Seminar Dr Mieke Van Lijsebettens 24/9 CANCELLED
by Delphine Verspeel 04 Sep '12

04 Sep '12

Dear All, The seminar of Dr Mieke Van Lijsebettens is cancelled. Kind regards, Delphine ___________________________________________ Delphine Verspeel Administrative Assistant VIB, Department of Plant Systems Biology Ghent University Technologiepark 927 9052 Gent Belgium Phone: +32/9/33.13.800 Fax: +32/9/33.13.809 Http://www.psb.ugent.be despe(a)psb.vib-ugent.be

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POSTDOC INNOVATION SEMINAR Prof Alexander Vainstein 06/09
by Delphine Verspeel 21 Aug '12

21 Aug '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at <https://maillist.psb.ugent.be/mailman/listinfo/seminars> https://maillist.psb.ugent.be/mailman/listinfo/seminars. If you do not wish to receive this information anymore, please unsubscribe from future mailings at <https://maillist.psb.ugent.be/mailman/options/seminars> https://maillist.psb.ugent.be/mailman/options/seminars. cid:946540515@15122008-0D1C PSB cid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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POSTDOC INNOVATION SEMINAR Prof Alexander Vainstein 06/09
by Delphine Verspeel 21 Aug '12

21 Aug '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at <https://maillist.psb.ugent.be/mailman/listinfo/seminars> https://maillist.psb.ugent.be/mailman/listinfo/seminars. If you do not wish to receive this information anymore, please unsubscribe from future mailings at <https://maillist.psb.ugent.be/mailman/options/seminars> https://maillist.psb.ugent.be/mailman/options/seminars. cid:946540515@15122008-0D1C PSB cid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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Upcoming seminars September
by Delphine Verspeel 21 Aug '12

21 Aug '12

Dear All, Enclosed you can find our upcoming seminars for September. Kind regards, Delphine ___________________________________________ Delphine Verspeel Administrative Assistant VIB, Department of Plant Systems Biology Ghent University Technologiepark 927 9052 Gent Belgium Phone: +32/9/33.13.800 Fax: +32/9/33.13.809 Http://www.psb.ugent.be despe(a)psb.vib-ugent.be

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PSB event reminder
by contact＠psb.vib-ugent.be 02 Jul '12

02 Jul '12

Calendar Name: seminars Scheduled for: Monday, July 2 2012, 11:00 - 12:30 Event text: Dr Javier Palatnik IBR (Instituto de Biologia Molecuar y Celular de Rosario) Rosario ARGENTINA Details: �microRNA biogenesis and function in plants� ABSTRACT MicroRNAs are small RNAs of ~21 nt that recognize partially complementary sites in target mRNAs and guide them to cleavage or translational arrest. The microRNAs are distinguished from other small RNAs by their unique biogenesis, which involves a precise excision from the stem of a fold-back precursor located in a long primary transcript. The type III ribonuclease DICER-LIKE1 (DCL1) with the aid of the accessory proteins cleaves the precursors to release the microRNAs. However, plant microRNA precursors come in variable sizes and shapes, and we are interested in understanding how these different precursors can be processed to generate the mature microRNAs. We have found that many precursors are processed in a base-to-loop direction, while others are processed by a non-canonical loop-to-base mechanism. We use a combination of approaches to study microRNA processing, including the analysis of libraries of random mutant precursors and the identification of processing intermediates with the aid of next generation sequencing techniques. In plants, many of the evolutionary conserved miRNAs regulate transcription factors, which in turn play key biological functions. Perturbation of these miRNA regulatory networks, by mutations in microRNA encoding genes or by interference with their activity usually causes severe developmental defects. We are interested in identifying the targets of plant microRNAs, as well as their biological functions. The lab specifically focuses in the control of cell proliferation and differentiation by two microRNAs, miR396 and miR319. Related Publications: Bologna, N.G., Mateos, J., Bresso, E.G., and Palatnik, J.F.. (2009) A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159. EMBO J, 28:3646-56. Mateos, J., Bologna, N.G., Chorostecki, U., and Palatnik, J.F. (2010) Identification of Structural Determinants for MicroRNA Processing in Plants by Random Mutagenesis of MIR172a Precursor. Current Biology, 20:49-54. Rodriguez, R., Mecchia, M., Debernardi, J.M., Schommer, C., Weigel, D., and Palatnik, J.F. (2010) Control of cell proliferation by microRNA miR396. Development, 137:103-12. Debernardi, J.M., Rodriguez, R.E., Mecchia, M., and Palatnik, J.F. (2012) Functional specialization of the plant miR396 regulatory network through distinct microRNA-target interactions, PLoS Genetics, 8: e1002419. Chorostecki, U., Crosa, V.C., Lodeyro, A.F., Bologna, N.G., Martin, A.P., Carrillo, C., Schommer, C. and Palatnik, J.F. (2012) Identification of new microRNA-regulated genes by conserved targeting in plant species, in press.

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PSB event reminder
by contact＠psb.vib-ugent.be 30 Jun '12

30 Jun '12

Calendar Name: seminars Scheduled for: Monday, July 2 2012, 11:00 - 12:30 Event text: Dr Javier Palatnik IBR (Instituto de Biologia Molecuar y Celular de Rosario) Rosario ARGENTINA Details: �microRNA biogenesis and function in plants� ABSTRACT MicroRNAs are small RNAs of ~21 nt that recognize partially complementary sites in target mRNAs and guide them to cleavage or translational arrest. The microRNAs are distinguished from other small RNAs by their unique biogenesis, which involves a precise excision from the stem of a fold-back precursor located in a long primary transcript. The type III ribonuclease DICER-LIKE1 (DCL1) with the aid of the accessory proteins cleaves the precursors to release the microRNAs. However, plant microRNA precursors come in variable sizes and shapes, and we are interested in understanding how these different precursors can be processed to generate the mature microRNAs. We have found that many precursors are processed in a base-to-loop direction, while others are processed by a non-canonical loop-to-base mechanism. We use a combination of approaches to study microRNA processing, including the analysis of libraries of random mutant precursors and the identification of processing intermediates with the aid of next generation sequencing techniques. In plants, many of the evolutionary conserved miRNAs regulate transcription factors, which in turn play key biological functions. Perturbation of these miRNA regulatory networks, by mutations in microRNA encoding genes or by interference with their activity usually causes severe developmental defects. We are interested in identifying the targets of plant microRNAs, as well as their biological functions. The lab specifically focuses in the control of cell proliferation and differentiation by two microRNAs, miR396 and miR319. Related Publications: Bologna, N.G., Mateos, J., Bresso, E.G., and Palatnik, J.F.. (2009) A loop-to-base processing mechanism underlies the biogenesis of plant microRNAs miR319 and miR159. EMBO J, 28:3646-56. Mateos, J., Bologna, N.G., Chorostecki, U., and Palatnik, J.F. (2010) Identification of Structural Determinants for MicroRNA Processing in Plants by Random Mutagenesis of MIR172a Precursor. Current Biology, 20:49-54. Rodriguez, R., Mecchia, M., Debernardi, J.M., Schommer, C., Weigel, D., and Palatnik, J.F. (2010) Control of cell proliferation by microRNA miR396. Development, 137:103-12. Debernardi, J.M., Rodriguez, R.E., Mecchia, M., and Palatnik, J.F. (2012) Functional specialization of the plant miR396 regulatory network through distinct microRNA-target interactions, PLoS Genetics, 8: e1002419. Chorostecki, U., Crosa, V.C., Lodeyro, A.F., Bologna, N.G., Martin, A.P., Carrillo, C., Schommer, C. and Palatnik, J.F. (2012) Identification of new microRNA-regulated genes by conserved targeting in plant species, in press.

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Seminar Dr Javier Palatnik 2/7
by Delphine Verspeel 22 Jun '12

22 Jun '12

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at <https://maillist.psb.ugent.be/mailman/listinfo/seminars> https://maillist.psb.ugent.be/mailman/listinfo/seminars. If you do not wish to receive this information anymore, please unsubscribe from future mailings at <https://maillist.psb.ugent.be/mailman/options/seminars> https://maillist.psb.ugent.be/mailman/options/seminars. cid:946540515@15122008-0D1C PSB cid:946540515@15122008-0D23 VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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Upcoming seminar July
by Delphine Verspeel 22 Jun '12

22 Jun '12

Dear All, Enclosed you can find our upcoming seminar for July. Kind regards, Delphine ___________________________________________ Delphine Verspeel Administrative Assistant VIB, Department of Plant Systems Biology Ghent University Technologiepark 927 9052 Gent Belgium Phone: +32/9/33.13.800 Fax: +32/9/33.13.809 Http://www.psb.ugent.be despe(a)psb.vib-ugent.be

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PSB event reminder
by contact＠psb.vib-ugent.be 21 Jun '12

21 Jun '12

Calendar Name: seminars Scheduled for: Thursday, June 21 2012, 11:00 - 12:30 Event text: Prof Pierre Hilson VIB, Dept. of Plant Systems Biology Ghent University Gent BELGIUM Details: �Signaling peptides regulate plant tropic growth and root development� ABSTRACT: Plant growth and development are coordinated by an array of intercellular signals, including phytohormones and secreted peptides. A cursory analysis of plant genomes suggests that the role of the latter class of molecules may still be underestimated. Furthermore, while both classes can be implicated in the same developmental processes, little is known about the interplay between phytohormone action and peptide signaling within the cellular microenvironment. We have shown that plant-specific genes coding for small secretory peptides, designated GOLVEN (GLV), modulate the distribution of the phytohormone auxin in Arabidopsis. The deregulation of the GLV function impairs the formation of auxin gradients via PIN proteins, thereby altering the reorientation of shoots and roots after a gravity stimulus, affecting meristem size, or preventing the proper development of lateral roots. We have also identified proteolytic enzymes important for the production of the bioactive GLV signal and will discuss their potential regulation. A complementary research project will be introduced. We have built a high-content screening platform to study the cellular phenotypes of isolated plant cells. This system has been optimized to track the proliferation of isolated Arabidopsis cells with high-throughput and robotized protocols. The properties of several molecules identified in large-scale screens will be described.

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PSB event reminder
by contact＠psb.vib-ugent.be 19 Jun '12

19 Jun '12

Calendar Name: seminars Scheduled for: Thursday, June 21 2012, 11:00 - 12:30 Event text: Prof Pierre Hilson VIB, Dept. of Plant Systems Biology Ghent University Gent BELGIUM Details: �Signaling peptides regulate plant tropic growth and root development� ABSTRACT: Plant growth and development are coordinated by an array of intercellular signals, including phytohormones and secreted peptides. A cursory analysis of plant genomes suggests that the role of the latter class of molecules may still be underestimated. Furthermore, while both classes can be implicated in the same developmental processes, little is known about the interplay between phytohormone action and peptide signaling within the cellular microenvironment. We have shown that plant-specific genes coding for small secretory peptides, designated GOLVEN (GLV), modulate the distribution of the phytohormone auxin in Arabidopsis. The deregulation of the GLV function impairs the formation of auxin gradients via PIN proteins, thereby altering the reorientation of shoots and roots after a gravity stimulus, affecting meristem size, or preventing the proper development of lateral roots. We have also identified proteolytic enzymes important for the production of the bioactive GLV signal and will discuss their potential regulation. A complementary research project will be introduced. We have built a high-content screening platform to study the cellular phenotypes of isolated plant cells. This system has been optimized to track the proliferation of isolated Arabidopsis cells with high-throughput and robotized protocols. The properties of several molecules identified in large-scale screens will be described.

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