[BBC] postdoctoral position in bioinformatics in University of Groningen

[Horvatovich, P.L.]

Postdoc research position LC-MS/MS data preprocessing and statistical
analysis (216165)



Organisation

The Faculty of Mathematics and Natural Sciences harbours a kaleidoscope of
disciplines and research strengths. Our programmes in research and
education range from nanomaterials and biomachinery to astronomy, from
mathematics to pharmacy, from neurosciences to computer science, and from
molecular and evolutionary biology to marine biology.
Our researchers pursue fundamental key questions while collaborating with
partners from industry, the medical world and other realms of society.
Frontline research groups explore new fields such as synthetic biologyand
sustainable energy use.

Job description

Development of single-stage LC-MS/MS data preprocessing and statistical
analysis approaches for risk assessment of mycotoxin exposure through
dietary intake in Qatar.

This postdoctoral position is embedded within the interdisciplinary
research groups of Analytical Biochemistry/Department of Pharmacy1 at the
Faculty of Mathematics and Natural Science of the University of Groningen
(RUG).

Mycotoxins are the most ubiquitous carcinogenic contaminant in the human
food supply leading to adverse consequences on human population such as
hepatocellular carcinoma. Mycotoxin concentrations are regularly measured
in food but their impact on human population health remain unclear. The aim
of this project is to perform risk assessment of mycotoxin exposure of
Qatar population through dietary intake in collaboration with scientists of
the Anti Doping Lab Qatar2.
In the research project the postdoctoral scientist is expected i) to
develop and implement novel single stage, data dependent and data
independent LC-MS(/MS) data pre-processing workflows based on Threshold
Avoiding Proteomics3 pipeline and other open source tool such as OpenMS4,
XCMS5 and mzMine6, and ii) statistical analysis of obtained molecular
profile for mycotoxin exposure in pilot animal study and in human
population and iii) perform risk assessment of human population in Qatar
based on obtained data.
The successful candidate will strongly benefit from working in a highly
interdisciplinary research team composed of clinical researchers,
analytical chemists, bioinformaticians and statisticians. The Analytical
Biochemistry group has an excellent scientific infrastructure and track
record in proteomics, proteogenomics and computational Mass Spectrometry1.

Qualifications

The candidate should have a strong background in mathematics and statistics
and should have strong experience in C++, Matlab and/or R programming.
Experience with data analysis in mass spectrometry would be a significant
advantage. The candidate should be able to work in an interdisciplinary and
multinational research team and have good communication skills.

Conditions of employment

The University of Groningen offers a salary that is determined in
accordance with the rules as set out in the collective labour agreement for
the Dutch Universities (CAO) and has a range between € 3,044 and € 3,997
(scale 10 Dutch Universities) gross per month depending on qualifications
and experience based on a fulltime position. The position is temporary for
one year. After a positive successful evaluation in the first year, the
contract will be extended by 1.5 year.
The University of Groningen offers an excellent research infrastructure and
training programme to develop research skills of the successful candidate.

Link references:
1 http://www.biomac.nl
2 http://adlqatar.net/
3 Suits F, Hoekman B, Rosenling T, Bischoff R, Horvatovich P.,
Threshold-avoiding proteomics pipeline, Anal Chem. 2011, 15;83(20):7786-94.
4 Bertsch A, Gröpl C, Reinert K, Kohlbacher O., OpenMS and TOPP: open
source software for LC-MS data analysis, Methods Mol Biol. 2011;696:353-67.
5 Mahieu NG, Genenbacher JL, Patti GJ., A roadmap for the XCMS family of
software solutions in metabolomics, Curr Opin Chem Biol., 2016, 30:87-93.
6 Pluskal T, Castillo S, Villar-Briones A, Oresic M., MZmine 2: modular
framework for processing, visualizing, and analyzing mass
spectrometry-based molecular profile data, BMC Bioinformatics. 2010, 11:395.

Additional information and sending in of applications
Applications with curriculum vitae and the names of three former or present
supervisors who can be contacted as references should be sent until 14 July
/ before 15 July 2016 Dutch local time by means of the application form
(click on the link below).

Unsolicited marketing is not appreciated.

Information

For information you can contact:

· Prof. P.L. Horvatovich, +31 50 3633341, p.l.horvatovich at rug.nl

(please do not use for applications)

*Apply
<http://www.rug.nl/about-us/work-with-us/job-opportunities/overview?reply=00347-02S0004ZFP>*

or direct link:

http://www.rug.nl/about-us/work-with-us/job-opportunities/overview?reply=00347-02S0004ZFP



-- 

Peter Horvatovich
Associate Professor

University of Groningen
Faculty of Mathematics and Natural Sciences
Department of Pharmacy
Analytical Biochemistry

Building 3226, Room 6.9
Antonius Deusinglaan 1
9713 AV Groningen
Internal Zip Code XB20
P.O. Box 196
9700 AD Groningen
The Netherlands

Telephone: +31-(0)50-363 3341
Fax: +31 (0)50 363 7582
Mobile: +31 (0)6 2459 7203
Email: p.l.horvatovich at rug.nl
Homepage: www.biomac.nl
-------------- next part --------------
An HTML attachment was scrubbed...
URL: <http://maillist.psb.ugent.be/pipermail/bbclist/attachments/20160620/2e3be0db/attachment.html>