[BBC] BioSB course Integrated Modeling and Optimization, 12-16 December 2022, Wageningen, the Netherlands
Celia van Gelder
celia.van.gelder at dtls.nl
Fri Nov 4 12:54:42 CET 2022
Dear colleagues,
Also in this academic year the BioSB research school, Wageningen
University & Reserach
and Eindhoven University of Technology will organize the course:
*Integrated Modeling and Optimization*
12-16 December 2022, Wageningen University
Website: https://www.dtls.nl/courses/integrated-modeling-and-optimization-2022/
Computational modelling is an absolute requisite to gain understanding of
the biological mechanisms underlying patterns observed in experimental
data. However, one could say that modelling is a craftsmanship, that can
only be learned via intense exercising and ‘learning by doing’. In this
course we offer the participants the possibility to learn and exercise the
modeling process and the optimization techniques needed to fit models to
data.
In the course the students will learn:
- to understand the common ground and the differences for applications
of dynamic modeling in metabolic, regulatory, signaling, and multi-scale
biological processes
- how to set-up a dynamic model to represent biological networks using
different interaction mechanisms
- to implement, simulate and analyze dynamic network models
- to understand the wide variety of problems in modelling that can be
solved with optimization ·
- to apply different types of numerical optimization methods: global and
local search methods: steepest descent, Levenberg-Marquardt, genetic
algorithms, linear programming.
- the combination of dynamic modeling and optimization to integrate
experimental data in modelling, estimate model parameters and design
experiments.
- to understand how numerical optimization (linear programming) works in
flux balance analysis to simulate metabolic network models.
Lecturers:
· Prof. Natal van Riel, Eindhoven University of Technology
(course coordinator)
· Dr. Aalt-Jan van Dijk, Wageningen University & Research
· Prof. Jaap Molenaar, Wageningen University & Research
· Dr. Hans Stigter, Wageningen University & Research
· Dr. Robert Smith, Wageningen University & Research
· Dr. Dragan Bosnacki, Eindhoven University of Technology
Target audience:
The course is aimed at PhD students with a background in
bioinformatics, systems biology, computer science or a related field,
and life sciences. Participants from the private sector are also
welcome. A working knowledge of mathematics,
especially differential equations, is recommendable, but we will
distribute preparation material to be studied by students
missing the required background. Furthermore, at the start we offer a
math refresher to help those participants who
are not (yet) involved in modelling on a daily basis.
--
Dr. Celia W.G. van Gelder
Training Programme Manager DTL/ELIXIR-NL/Health-RI
Network Manager TDCC-LSH
tel. +31613375327
e-mail: celia.van.gelder at dtls.nl
websites: https://www.dtls.nl/, https://www.health-ri.nl/,
https://www.elixir-europe.org/platforms/training
twitter: celia_vgelder
Office: DTL | Jaarbeurs Innovation Mile (JIM) | 6th floor
Beatrixgebouw | Jaarbeursplein 6 | 3521 AL Utrecht
While I may be sending this email outside my normal office hours, I have no
expectation to receive a reply outside yours.
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