- Seminars - maillist.psb.ugent.be

PSB event reminder
by contact＠psb.vib-ugent.be 15 Dec '10

15 Dec '10

Calendar Name: seminars Scheduled for: Friday, December 17 2010, 11:00 - 12:30 Event text: Alexis Maizel Department of Stem Cell Biology Center for organismal studies University of Heidelberg Heidelberg GERMANY Details: "Control of developmental plasticity and robustness by small RNAs in Arabidopsis" ABSTRACT Plants adapt to their environment by forming new organs throughout their entire postembryonic life. The harmonious growth of these organs in response to morphogenetic signals is essential. Lateral roots unceasingly branch from the main root in response to local auxin maxima. How a local maximum translates to a robust pattern of gene activation ensuring the proper growth of the newly formed root is not known. The TAS3-derived trans-acting siRNAs (ta-siRNAs) belong to a plant-specific class of endogenous small RNAs, whose biogenesis requires the initial microRNA 390 (miR390)-mediated cleavage of the TAS3 precursor by AGO7. The ta-siRNAs target mRNAs encoding ARF3/ETTIN and ARF4 which are transcription factors of the AUXIN RESPONSE FACTORs that mediate the effects of auxin. I will present recent results establishing that auxin maxima at the sites of lateral root initiation promote localised production of miR390, allowing the formation of ta-siARFs to subsequently inhibit ARF3/4 activity in the incipient primordia. In turn, ARF3 and ARF4 contribute both positively and negatively to miR390 accumulation. These results support a model in which small RNAs employ target genes to regulate their own production.

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PSB event reminder
by contact＠psb.vib-ugent.be 07 Dec '10

07 Dec '10

Calendar Name: seminars Scheduled for: Tuesday, December 7 2010, 10:00 - 11:00 Event text: Klaas Vandepoele VIB, Dept. of Plant Systems Biology Ghent University BELGIUM Details: "Transferring gene functions between different plant species using PLAZA 2.0" ABSTRACT PLAZA is an online comparative genomics platform where data generated by different plant sequencing initiatives is integrated and combined with advanced methods for data mining. This resource includes structural and functional annotation of published plant genomes together with a large set of interactive tools to study gene function and gene and genome evolution. Pre-computed data sets cover homologous gene families, multiple sequence alignments, phylogenetic trees, intra-species whole-genome dot plots, and genomic colinearity between species. The Workbench provides an efficient environment to analyze user-defined gene sets using PLAZA's interface including GO enrichment analysis for all species. The second release of this resource integrates whole-genome information from 23 plants covering 11 dicots, 5 monocots, 2 (club-)mosses and 5 algae (>840,000 genes stored in >22,000 multi-species gene families). New features include functional gene clustering based on GO annotations, interactive Syntenty plots to study the gene organization of homologous genes and the reliable identification of orthologous genes (through the integration of a complementary set of data types). During this presentation I will elaborate on different methodologies to identify orthologous genes in different species, discuss pitfalls inherent to simple ad-hoc approaches to identify 'functional homologs' and demonstrate how PLAZA 2.0 can facilitate the transfer of functional information between plants. PLAZA 2.0 is available at http://bioinformatics.psb.ugent.be/plaza/.

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PSB event reminder
by contact＠psb.vib-ugent.be 05 Dec '10

05 Dec '10

Calendar Name: seminars Scheduled for: Tuesday, December 7 2010, 10:00 - 11:00 Event text: Klaas Vandepoele VIB, Dept. of Plant Systems Biology Ghent University BELGIUM Details: "Transferring gene functions between different plant species using PLAZA 2.0" ABSTRACT PLAZA is an online comparative genomics platform where data generated by different plant sequencing initiatives is integrated and combined with advanced methods for data mining. This resource includes structural and functional annotation of published plant genomes together with a large set of interactive tools to study gene function and gene and genome evolution. Pre-computed data sets cover homologous gene families, multiple sequence alignments, phylogenetic trees, intra-species whole-genome dot plots, and genomic colinearity between species. The Workbench provides an efficient environment to analyze user-defined gene sets using PLAZA's interface including GO enrichment analysis for all species. The second release of this resource integrates whole-genome information from 23 plants covering 11 dicots, 5 monocots, 2 (club-)mosses and 5 algae (>840,000 genes stored in >22,000 multi-species gene families). New features include functional gene clustering based on GO annotations, interactive Syntenty plots to study the gene organization of homologous genes and the reliable identification of orthologous genes (through the integration of a complementary set of data types). During this presentation I will elaborate on different methodologies to identify orthologous genes in different species, discuss pitfalls inherent to simple ad-hoc approaches to identify 'functional homologs' and demonstrate how PLAZA 2.0 can facilitate the transfer of functional information between plants. PLAZA 2.0 is available at http://bioinformatics.psb.ugent.be/plaza/.

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seminar Alexis Maizel 17/12
by Nathalie Vanden Hautte 02 Dec '10

02 Dec '10

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at https://maillist.psb.ugent.be/mailman/listinfo/seminars <https://maillist.psb.ugent.be/mailman/listinfo/seminars> . If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/options/seminars <https://maillist.psb.ugent.be/mailman/options/seminars> . VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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FW: upcoming seminars December
by Nathalie Vanden Hautte 02 Dec '10

02 Dec '10

Dear All Enclosed the updated list for December. Kind regards Nathalie From: Nathalie Vanden Hautte Sent: donderdag 25 november 2010 11:09 To: 'meetings(a)psb.vib-ugent.be' Subject: upcoming seminars December Dear All Enclosed you can find our upcoming seminars for December. Kind regards Nathalie ____________________________________________ Nathalie Vanden Hautte Administrative Assistant VIB, Department of Plant Systems Biology Ghent University Technologiepark 927 9052 Gent Belgium Phone: +32/9/33.13.800 Fax: +32/33.13.809 Http://www.psb.ugent.be nahau(a)psb.vib-ugent.be

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PSB event reminder
by contact＠psb.vib-ugent.be 02 Dec '10

02 Dec '10

Calendar Name: seminars Scheduled for: Thursday, December 2 2010, 11:00 - 12:30 Event text: Pascal Genschik Institut de Biologie Mol�culaire des Plantes du CNRS IBMP-CNRS - UPR2357 Strasbourg FRANCE Details: "CUL4-DDB1 is required to maintain epigenetic gene repression via its interaction with the Arabidopsis PRC2 complex" ABSTRACT Protein ubiquitylation regulates a broad variety of biological processes in all eukaryotes. Recent work identified a novel class of cullin-RING ligase (CRL) composed of CUL4, DDB1, and one substrate receptor also called DCAF (DDB1 and CUL4-associated factors). DCAFs are WD40 proteins containing WDxR motifs that are required for efficient binding to DDB1. In both human and Arabidopsis, about 90 different DCAFs have been predicted, but for most of them their function or substrates remain still unknown. Among putative Arabidopsis DCAFs we identified MSI1, which belongs to an evolutionary conserved protein family. MSI1-like proteins contribute to different protein complexes, including the epigenetic regulatory Polycomb Repressive Complex2 (PRC2). Here we will present evidence that Arabidopsis MSI1 physically interacts with DDB1 and is part of a multimeric CRL4-type E3 complex. Interestingly the CUL4-DDB1MSI1 complex is required to maintain parental imprinting of MEA, a target gene of the Arabidopsis PRC2 complex. Moreover, we extended these studies to another MSI1-like protein, called MSI4/FVE, which is involved in the regulation of flowering time. Overall, we will discuss the mechanism by which CRL4s are required to maintain Polycomb-mediated gene repression.

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PSB event reminder
by contact＠psb.vib-ugent.be 30 Nov '10

30 Nov '10

Calendar Name: seminars Scheduled for: Thursday, December 2 2010, 11:00 - 12:30 Event text: Pascal Genschik Institut de Biologie Mol�culaire des Plantes du CNRS IBMP-CNRS - UPR2357 Strasbourg FRANCE Details: "CUL4-DDB1 is required to maintain epigenetic gene repression via its interaction with the Arabidopsis PRC2 complex" ABSTRACT Protein ubiquitylation regulates a broad variety of biological processes in all eukaryotes. Recent work identified a novel class of cullin-RING ligase (CRL) composed of CUL4, DDB1, and one substrate receptor also called DCAF (DDB1 and CUL4-associated factors). DCAFs are WD40 proteins containing WDxR motifs that are required for efficient binding to DDB1. In both human and Arabidopsis, about 90 different DCAFs have been predicted, but for most of them their function or substrates remain still unknown. Among putative Arabidopsis DCAFs we identified MSI1, which belongs to an evolutionary conserved protein family. MSI1-like proteins contribute to different protein complexes, including the epigenetic regulatory Polycomb Repressive Complex2 (PRC2). Here we will present evidence that Arabidopsis MSI1 physically interacts with DDB1 and is part of a multimeric CRL4-type E3 complex. Interestingly the CUL4-DDB1MSI1 complex is required to maintain parental imprinting of MEA, a target gene of the Arabidopsis PRC2 complex. Moreover, we extended these studies to another MSI1-like protein, called MSI4/FVE, which is involved in the regulation of flowering time. Overall, we will discuss the mechanism by which CRL4s are required to maintain Polycomb-mediated gene repression.

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seminar Pascal Genschik 02/12
by Nathalie Vanden Hautte 25 Nov '10

25 Nov '10

You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at https://maillist.psb.ugent.be/mailman/listinfo/seminars <https://maillist.psb.ugent.be/mailman/listinfo/seminars> . If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/options/seminars <https://maillist.psb.ugent.be/mailman/options/seminars> . VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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upcoming seminars December
by Nathalie Vanden Hautte 25 Nov '10

25 Nov '10

Dear All Enclosed you can find our upcoming seminars for December. Kind regards Nathalie ____________________________________________ Nathalie Vanden Hautte Administrative Assistant VIB, Department of Plant Systems Biology Ghent University Technologiepark 927 9052 Gent Belgium Phone: +32/9/33.13.800 Fax: +32/33.13.809 Http://www.psb.ugent.be nahau(a)psb.vib-ugent.be

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FW: seminar Raf Roelands & Philippe Gabant 24/11
by Nathalie Vanden Hautte 24 Nov '10

24 Nov '10

REMINDER From: Nathalie Vanden Hautte [mailto:nahau@psb.vib-ugent.be] Sent: donderdag 4 november 2010 16:12 To: _users(a)dmbr.ugent.be; meetings(a)psb.vib-ugent.be Subject: seminar Raf Roelands & Philippe Gabant 24/11 You are receiving this e-mail because you subscribed to our seminars announcements and reminders service at https://maillist.psb.ugent.be/mailman/listinfo/seminars <https://maillist.psb.ugent.be/mailman/listinfo/seminars> . If you do not wish to receive this information anymore, please unsubscribe from future mailings at https://maillist.psb.ugent.be/mailman/options/seminars <https://maillist.psb.ugent.be/mailman/options/seminars> . VIB - Department of Plant Systems Biology Technologiepark 927 B - 9052 Gent/Zwijnaarde Phone: +32 9 33 13 800 Fax: +32 9 33 13 809 Http://www.psb.vib-ugent.be

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